Transcriptomics

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Expression data from undifferentiated human ES cell line, khES3, grown using complete or methionine deprived media and ES cell derived endoderm


ABSTRACT: In undifferentiated human ES cells, 5hr Met deprivation (delta Met) led to decreased proliferation, and prolonged 24hr Met deprivation resulted in G0-G1 phase cell cycle arrest, which then led to apoptosis. We used microarrays to detail the molecular mechanism of cell-death caused by Met deprivation in undifferentiated ES cells and checked the difference of Met cycle relate gene expression between undifferentiated human ES cells and ES cell derived endoderm.

ORGANISM(S): Homo sapiens

PROVIDER: GSE55283 | GEO | 2014/04/17

SECONDARY ACCESSION(S): PRJNA239200

REPOSITORIES: GEO

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