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Microarray analysis of cultured gastric myofibroblasts

ABSTRACT: Neuronal, endocrine and exocrine cells exhibit regulated exocytosis but there is also a body of evidence for regulated exocytosis from other cell types. Myofibroblasts are a stromal cell type that secretes extracellular matrix proteins, growth factors and cytokines; they are important in wound healing and increasingly are recognised to play a role in modifying the cellular microenvironment in cancer. We have established calcium dependent regulated secretion in a subset of myofibroblasts from gastric cancers, adjacent tissue and from normal tissue. We have used microarrays to look for the expression of genes associated with the regulated secretory phenotype.

ORGANISM(S): Homo sapiens

PROVIDER: GSE44740 | GEO | 2013/02/28

SECONDARY ACCESSION(S): PRJNA191158

REPOSITORIES: GEO

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Microarray analysis of cultured gastric myofibroblasts

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