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Treatment of established mouse AA with topical JAK inhibitors

ABSTRACT: Our goal was to identify gene expression patterns that correlated with treatment of established autoimmune alopecia in C3H/HeJ mice following alopecic graft transplantation skin from 3 mice were taken at 6, 12 and, in some cases, 24 weeks of topical drug administration following grafting; mice were treated with ruxolitinib (jak1i), tofacitinib (jak3i), or control pbs

ORGANISM(S): Mus musculus

PROVIDER: GSE45514 | GEO | 2014/08/17

SECONDARY ACCESSION(S): PRJNA194536

REPOSITORIES: GEO

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Treatment of established mouse AA with topical JAK inhibitors

Project description:Our goal was to identify gene expression patterns that correlated with treatment of established autoimmune alopecia in C3H/HeJ mice following alopecic graft transplantation skin from 3 mice were taken at 6, 12 and, in some cases, 24 weeks of topical drug administration following grafting; mice were treated with ruxolitinib (jak1i), tofacitinib (jak3i), or control pbs 3 biological replicates were taken at each time point for each treatment modality

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