Genomics

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Identification of miRNAs specific for prostate cancer (PCa)


ABSTRACT: The purpose of this study are: - To identify new biomarkers specific for prostate cancer (PCa) that can be used as diagnostic markers in the urine of individuals with high probability of PCa (abnormal PSA and/or digital rectal examination). - To validate the utility of these new biomarkers, as well as others already known such as PCA3, fusion gene TMPRSS2-ERG, GOLPH2 and SPINK1. - To establish a prediction model for the diagnosis of PCa based on the expression of these biomarkers. - To validate this model within the framework of an opportunist programme of early diagnosis. - Within the framework of this programme, to associate a series of social-demographic, antropometric, life-style and occupational variables for establishing a risk model predictor that could be associated with the model based on the biomarkers.

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE45604 | GEO | 2013/03/29

SECONDARY ACCESSION(S): PRJNA195380

REPOSITORIES: GEO

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