Transcriptomics

Dataset Information

0

Transcriptome analysis during somatic cell reprogramming


ABSTRACT: By combining deep sequencing with high-throughput quantitative RT-PCR, we reveal that somatic splicing profiles are reorganized to pluripotent splicing profiles during reprogramming from mouse embryonic fibroblasts (MEFs) to induced pluripotent stem (iPS) cells. The splicing pattern in pluripotent stem cells resembles that in testis, and the regulatory regions have specific characters in length and sequence. These results indicate that the dynamic alteration in splicing is an integral part of the molecular network involved in the reprogramming process.

ORGANISM(S): Mus musculus

PROVIDER: GSE46149 | GEO | 2013/10/17

SECONDARY ACCESSION(S): PRJNA197366

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2013-10-17 | E-GEOD-46149 | biostudies-arrayexpress
2008-06-18 | E-GEOD-10871 | biostudies-arrayexpress
2008-05-28 | GSE10871 | GEO
2016-02-24 | PXD002769 | Pride
2010-05-15 | E-GEOD-13146 | biostudies-arrayexpress
2011-09-21 | E-GEOD-21595 | biostudies-arrayexpress
2014-07-05 | E-GEOD-52950 | biostudies-arrayexpress
2013-01-04 | GSE27206 | GEO
2013-01-04 | E-GEOD-27206 | biostudies-arrayexpress
2008-01-01 | GSE9071 | GEO