Transcriptomics

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The expression analyses of trisomy 2L compared with normal


ABSTRACT: Dosage compensation was referred as an equalized X chromosome gene expression between males and females in Drosophila. And inverse dosage effects, produced by genomic imbalance, are believed to account for this modulated expression. Here we made a global expression comparison of trisomy 2L with on extra copy of chromosome 2 long arm to normal diploid with two copies of 2L with high throughput RNA-sequencing. We want to test how about the gene expression pattern changes in those comparisons, including the genes on varied chromosome 2 long arm, some other autosomal genes except chromosome 2L and X chromosome genes. Dosage compensation with an expression level similar to normal diploid and inverse dosage effects should be detected.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE46354 | GEO | 2013/09/10

SECONDARY ACCESSION(S): PRJNA198800

REPOSITORIES: GEO

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