Transcriptomics

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Differential regulation of gene expression by two isoforms of the human transcriptional coactivator MKL1


ABSTRACT: We identified two isoforms of human MKL1 that differ in their N-terminal domains. Since MKL1 is a transcriptional coactivator of SRF and regulates many SRF target genes, we wanted to analyze if transcription is differentially regulated by the two isoforms upon stimulation of the Rho-actin-MKL1-SRF pathway.

ORGANISM(S): Homo sapiens

PROVIDER: GSE47209 | GEO | 2015/05/14

SECONDARY ACCESSION(S): PRJNA205115

REPOSITORIES: GEO

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