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Expression analysis of mock- or RAD21-transduced Kasumi1 cells

ABSTRACT: We recently identified recurrent mutations of cohesin complex in myeloid neoplasms through whole-exome sequencing analysis. RAD21 is one of the main components of the cohesin complex. In this study, to investigate the biological impact of wild-type RAD21 on Kasumi1 cells harboring RAD21 mutation, Kasumi1 cells were retrovirally transduced with either mock or wild-type RAD21, and expression array was performed.

ORGANISM(S): Homo sapiens

PROVIDER: GSE47641 | GEO | 2013/07/16

SECONDARY ACCESSION(S): PRJNA207003

REPOSITORIES: GEO

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Expression analysis of mock- or RAD21-transduced Kasumi1 cells

Project description:We recently identified recurrent mutations of cohesin complex in myeloid neoplasms through whole-exome sequencing analysis. RAD21 is one of the main components of the cohesin complex. In this study, to investigate the biological impact of wild-type RAD21 on Kasumi1 cells harboring RAD21 mutation, Kasumi1 cells were retrovirally transduced with either mock or wild-type RAD21, and expression array was performed. Expression analysis was performed for mock- or wild-type RAD21-transduced Kasumi-1 cells in triplicate. The experiment was performed twice independently.

2013-07-16 | E-GEOD-47641 | biostudies-arrayexpress

Rad21

Project description:Rattus norvegicus Rad21, RAD21 cohesin complex component [Source:RGD Symbol;Acc:1594529], is differentially expressed in 23 experiment(s);

| ENSRNOG00000004420 | ExpressionAtlas

RAD21

Project description:Monodelphis domestica RAD21, RAD21 cohesin complex component [Source:NCBI gene;Acc:100025333], is expressed in 2 baseline experiment(s);

| ENSMODG00000004133 | ExpressionAtlas

Rad21

Project description:Rattus norvegicus Rad21, RAD21 cohesin complex component [Source:RGD Symbol;Acc:1594529], is expressed in 6 baseline experiment(s);

| ENSRNOG00000004420 | ExpressionAtlas

RAD21

Project description:Sus scrofa RAD21, RAD21 cohesin complex component [Source:VGNC Symbol;Acc:VGNC:92054], is expressed in 5 baseline experiment(s);

| ENSSSCG00000006014 | ExpressionAtlas

rad21

Project description:Xenopus tropicalis rad21, RAD21 cohesin complex component [Source:Xenbase;Acc:XB-GENE-1008099], is expressed in 1 baseline experiment(s);

| ENSXETG00000020783 | ExpressionAtlas

RAD21

Project description:Macaca mulatta RAD21, RAD21 cohesin complex component [Source:VGNC Symbol;Acc:VGNC:84108], is expressed in 3 baseline experiment(s);

| ENSMMUG00000020285 | ExpressionAtlas

RAD21

Project description:Homo sapiens RAD21, RAD21 cohesin complex component [Source:HGNC Symbol;Acc:HGNC:9811], is differentially expressed in 157 experiment(s);

| ENSG00000164754 | ExpressionAtlas

RAD21

Project description:Oryctolagus cuniculus RAD21, RAD21 cohesin complex component [Source:HGNC Symbol;Acc:HGNC:9811], is expressed in 1 baseline experiment(s);

| ENSOCUG00000002581 | ExpressionAtlas

RAD21

Project description:Equus caballus RAD21, RAD21 cohesin complex component [Source:VGNC Symbol;Acc:VGNC:22144], is expressed in 1 baseline experiment(s);

| ENSECAG00000016392 | ExpressionAtlas

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