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Early life stress in fathers impairs synaptic plasticity in the offspring - brain collected at rest

ABSTRACT: We show that traumatic stress experienced by males in early postnatal life impairs memory in their offspring, blocks long-term potentiation (LTP) and favors long-term depression (LTD). These effects are accompanied by suppression of key molecular pathways involved in neuronal plasticity both at rest and after acute stress.

ORGANISM(S): Mus musculus

PROVIDER: GSE47846 | GEO | 2014/07/01

SECONDARY ACCESSION(S): PRJNA208122

REPOSITORIES: GEO

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