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Expression data from GGF2-treated post-MI swine

ABSTRACT: Neuregulin-1 (NRG-1) is a paracrine factor critical for cardiac development. We have been examining whether the recombinant NRG-1β isoform known as glial growth factor 2 (GGF2) has therapeutic potential for heart failure. In both small and large animals after experimental myocardial infarction (MI) we have found that GGF2 treatment improves myocardial function and limits progressive myocardial remodeling. To understand potential mechanisms for this effect, we compared gene expression in swine by microarray analysis. We used microarrays to compared th the global gene expression underlying the efficacy of GGF2 treatment for heart injury.

ORGANISM(S): Sus scrofa

PROVIDER: GSE48255 | GEO | 2014/06/21

SECONDARY ACCESSION(S): PRJNA209383

REPOSITORIES: GEO

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Expression data from GGF2-treated post-MI swine

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