Transcriptomics

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Expression data from hBMSCs cultured on PLLA nanofibers


ABSTRACT: Nanotopographic cues from biomaterials exert powerful effects on the osteogenic differentiation of mesenchymal stem cells because of their niche-mimicking features. However, the biological mechanisms underlying cell lineage determination by surface nanotopography have not been clearly elucidated. Here, we explored the osteogenic behavior of human bone marrow mesenchymal stem cells (hBMSCs) on PLLA nanofibers with different orientations, and monitored the dynamic changes in global gene expression triggered by topographical cues.

ORGANISM(S): Homo sapiens

PROVIDER: GSE48616 | GEO | 2014/09/01

SECONDARY ACCESSION(S): PRJNA210830

REPOSITORIES: GEO

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