Transcriptomics

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In vitro selection for chitosan-resistant Staphylococcus aureus - phenotypic and molecular characterisation of resistance development


ABSTRACT: A mutant of SG511 (wild type isolate), resistant to the presence of chitosan (polycationic molecule) was obtained following serial passage experiments resistance to chitosan exposition. Transcriptomic experiments showed alteration in the expression of genes involved in the cell wall regulon resulting in the modification of susceptibility phenotype against cell wall active antibiotics

ORGANISM(S): Staphylococcus aureus subsp. aureus N315 Staphylococcus aureus subsp. aureus COL Staphylococcus aureus subsp. aureus Mu50 Staphylococcus aureus subsp. aureus MRSA252 Staphylococcus aureus subsp. aureus USA300 Staphylococcus aureus subsp. aureus NCTC 8325 Staphylococcus aureus subsp. aureus MW2 Staphylococcus aureus subsp. aureus MSSA476 Staphylococcus aureus

PROVIDER: GSE48912 | GEO | 2014/07/15

SECONDARY ACCESSION(S): PRJNA212299

REPOSITORIES: GEO

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