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Insight into the response of Bacillus cereus towards the polysaccharide chitosan

ABSTRACT: Comparison of chitosan-treated B. cereus ATCC 14579 cells with non-treated B. cereus ATCC 14579 cells. 2 chitosans with similar molecular weight (Mw) but different degrees of acetylation (Fa) were used: chitosan B (Mw: 28.4 kDa, Fa: 0.16) (samples 1-3) and chitosan A (Mw: 36.0 kDa, Fa: 0.01) (samples 4-6). One-condition design comparision of treated vs. non-treated control. 3 biological replicates, including a dye swap.

ORGANISM(S): Bacillus cereus

SUBMITTER: Akos Kovacs

PROVIDER: E-GEOD-29024 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcriptional responses of Bacillus cereus towards challenges with the polysaccharide chitosan.

Mellegård Hilde H Kovács Ákos T ÁT Lindbäck Toril T Christensen Bjørn E BE Kuipers Oscar P OP Granum Per E PE

PloS one 20110908 9

The antibacterial activity of the polysaccharide chitosan towards different bacterial species has been extensively documented. The response mechanisms of bacteria exposed to this biopolymer and the exact molecular mechanism of action, however, have hardly been investigated. This paper reports the transcriptome profiling using DNA microarrays of the type-strain of Bacillus cereus (ATCC 14579) exposed to subinhibitory concentrations of two water-soluble chitosan preparations with defined chemical ...[more]

PMID: 21931677

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