Genomics

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Genomic characterization of three acute lymphoblastic leukemia cases and one established cell line REH at the single cell level


ABSTRACT: DNA copy number alterations and mutations were characterised by bulk SNP anlaysis and exome sequencing (not sown here) in three acute lymphoblastic leukaemia samples and one establish cell line REH. Further single cell experiments of these cases investigated the mutation and copy number targets previously defined exploring the sub-clonal populations and phylogenic trees within each leukaemia. Affymetrix SNP arrays were performed according to the manufacturer's directions on DNA extracted from cryopreserved diagnostic bone marrow or peripheral blood samples.

ORGANISM(S): Homo sapiens

PROVIDER: GSE49215 | GEO | 2013/07/26

SECONDARY ACCESSION(S): PRJNA213300

REPOSITORIES: GEO

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