Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

S. coelicolor, Control (untreated) Vs Ciprofloxacin treated

ABSTRACT: Transcriptional profiling of S. coelicolor comparing control untreated cells with ciprofloxacin treated cells. Two-condition experiment, Control Vs CIP treatment. Biological replicates: 3 control, One dye swap replicate.

ORGANISM(S): Streptomyces coelicolor Streptomyces coelicolor A3(2)

PROVIDER: GSE49788 | GEO | 2014/01/01

SECONDARY ACCESSION(S): PRJNA214909

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

S. coelicolor, Control (untreated) Vs Ciprofloxacin treated

Project description:Transcriptional profiling of S. coelicolor comparing control untreated cells with ciprofloxacin treated cells. Two-condition experiment, Control Vs CIP treatment. Biological replicates: 3 control, One dye swap replicate. four samples and three biological replicate to study the response of S. coleicolor cells to ciprofloxacin

2014-01-01 | E-GEOD-49788 | biostudies-arrayexpress

S. coelicolor, control (untreated) vs ciprofloxacin-treated

Project description:Transcriptional profiling of S. coelicolor cells treated with sub-inhibitory or inhibitory concentrations of ciprofloxacin in comparision to untreated control when cultured in R5 media. Two-condition experiment, Control Vs CIP treatment.

2019-06-01 | GSE115753 | GEO

S. coelicolor, control (untreated) vs ciprofloxacin-treated

Project description:S. coelicolor, control (untreated) vs ciprofloxacin-treated

| PRJNA475952 | ENA

Y. pestis exposed to various concentrations of ciprofloxacin for various time points (treated/nontreated analysis in each array).

Project description:Cultures of Y. pestis Kimberley53 virulent strain were exposed to different concentrations of ciprofloxacin (including 0.016 µg/ml representing the strains' MIC value) for various time periods. Total RNA samples were extructed and used for cRNA synthesis and labelling (using Cy3-CTP for the treated samples and Cy5-CTP for the non-treated sample in one biological experiment and dye swap for the 2nd replicate of independent biological experiment). 8 Labeled cRNA samples were hybridized to custom made Agilent 8x15K slide (each slide represent 1 time point). Goal: Identifing alterations in gene expression profile which correlates with the ciprofloxacin induced growth inhibition. Those altered mRNA transcrips will be used as a markers for the development of rapid molecular Antibiotic Susceptibility Test.

2016-03-30 | GSE79687 | GEO

Identification of ciprofloxacin helper drug targets by RNA-seq

Project description:The aim of this study was to identify genes that can be targeted by helper drugs to counteract resistance towards ciprofloxacin (CIP). In order to reveal the impact of ciprofloxacin on the transcriptome, differential gene-expression analysis by RNA-seq was performed on the multidrug resistant E. coli strain ST131, treated with a clinically relevant concentration of ciprofloxacin (2 µg/mL).

2016-11-04 | GSE89507 | GEO

Streptomyces coelicolor

Project description:S. coelicolor, Control (untreated) Vs Ciprofloxacin treated

| PRJNA214909 | ENA

Salmonella enteritidis ciprofloxacin resistance effect on transcription in LB

Project description:comparison of total RNA profiles obtained from ciprofloxacin resistant colonies of two separate Enteritidis isolates with their respective wt parents total RNA of both wt (with reduced cip sensitivity at MIC=0.2 ug/ml) and spontaneous cipR mutants (MIC>32ug/ml) in LB log phase was harvested from Enteritidis strain 104 (from poultry host) and Enteritidis 5408 (from human host), and compared on a PCR product array

2010-06-25 | E-GEOD-15024 | biostudies-arrayexpress

Y. pestis exposed to various concentrations of ciprofloxacin for various time points (treated/nontreated analysis in each array).

Project description:Cultures of Y. pestis Kimberley53 virulent strain were exposed to different concentrations of ciprofloxacin (including 0.016 Âµg/ml representing the strains' MIC value) for various time periods. Total RNA samples were extructed and used for cRNA synthesis and labelling (using Cy3-CTP for the treated samples and Cy5-CTP for the non-treated sample in one biological experiment and dye swap for the 2nd replicate of independent biological experiment). 8 Labeled cRNA samples were hybridized to custom made Agilent 8x15K slide (each slide represent 1 time point). Goal: Identifing alterations in gene expression profile which correlates with the ciprofloxacin induced growth inhibition. Those altered mRNA transcrips will be used as a markers for the development of rapid molecular Antibiotic Susceptibility Test. Y. perstis exposed to 0.001, 0.016, 0.5 and 4 Âµg/ml ciprofloxacin, compared to growth control (non treated) sample, for 3 time periods (45, 90 and 120 min.). Two independent biological replicates were performed. Extracted total RNA were used for cRNA synthesis and labeling with Cy3/Cy5-CTP, hybridized to Agilent custom-made 8x15K slide format.

2016-03-30 | E-GEOD-79687 | biostudies-arrayexpress

EV39+40 mRNA levels in Wild-type versus ddm1 Arabidopsis thaliana seedlings

Project description:Technical replicate of EV33+34. The two samples in this series are complementary hybridizations in a dye-swap analysis. Below is the normalized result of the paired dye swap samples EV39 and EV40. The ANOVA model of Kerr, Martin and Churchill (2000) was used to analyze the data from the dye-swap experiments, with terms included to account for gene, dye-by-gene, treatment-by-gene, and random error terms. To account for the number of hypothesis tests being made, and thus provide some level of error rate control, significance was assessed using a false discovery rate (FDR) controlling method. The step-up procedure of Benjamini and Hochberg (1995) was used to control the FDR below alpha = 0.01. For the purposes of this experiment, the hypotheses were assumed to be independent. Features found to be significantly enriched for DNA methylation after hypothesis-testing with a controlled error rate are flagged in the column. Standard errors and P-values are not available. Keywords: other

2004-06-12 | GSE1327 | GEO

VC109+111 mRNA levels in Wild-type versus ddm1 Arabidopsis thaliana seedlings

Project description:Biological replicate of EV33+34. The two samples in this series are complementary hybridizations in a dye-swap analysis. Below is the normalized result of the paired dye swap samples VC109 and VC110. The ANOVA model of Kerr, Martin and Churchill (2000) was used to analyze the data from the dye-swap experiments, with terms included to account for gene, dye-by-gene, treatment-by-gene, and random error terms. To account for the number of hypothesis tests being made, and thus provide some level of error rate control, significance was assessed using a false discovery rate (FDR) controlling method. The step-up procedure of Benjamini and Hochberg (1995) was used to control the FDR below alpha = 0.01. For the purposes of this experiment, the hypotheses were assumed to be independent. Features found to be significantly enriched for DNA methylation after hypothesis-testing with a controlled error rate are flagged in the column. Standard errors and P-values are not available. Keywords: other

2004-06-12 | GSE1326 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data