ChIP-seq assays for H3K27ac
Ontology highlight
ABSTRACT: By using FACS-sorted MC1-ZE7 ES cells, we analyzed the genome-wide distribution of H3K27ac and DNA methylation in Zscan4 positive ES cells (Em+) and Zscan4 negative ES cells (Em-). H3K27 hyperacetylation and DNA demethylation were detected in heterochromatic regions of Em+ cells, but not Em- cells. These results suggested that the Zscan4 state takes "open" chromatin conformation in ES cells.
ORGANISM(S): Mus musculus
PROVIDER: GSE51679 | GEO | 2015/09/10
SECONDARY ACCESSION(S): PRJNA224548
REPOSITORIES: GEO
ACCESS DATA