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Identification of the molecular targets of microRNA-181d in murine thymocytes.

ABSTRACT: T cell-specific transgenic expression of microRNA-181d reduced number of immature CD4+CD8+ thymocytes. Microarray analysis was performed to reveal differentially expressed genes between the wild type and microRNA-181d transgenic thymocytes.

ORGANISM(S): Mus musculus

PROVIDER: GSE51778 | GEO | 2014/01/21

SECONDARY ACCESSION(S): PRJNA225014

REPOSITORIES: GEO

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Identification of the molecular targets of microRNA-181d in murine thymocytes.

Project description:T cell-specific transgenic expression of microRNA-181d reduced number of immature CD4+CD8+ thymocytes. Microarray analysis was performed to reveal differentially expressed genes between the wild type and microRNA-181d transgenic thymocytes. Whole thymus tissues were isolated from the wild type (C57BL/6) and microRNA-181d transgenic mice (Tg-38 line), followed by total RNA isolation.

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