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Comparison of gene expression at day 11 of iPSC reprogramming with different reprogramming cocktails

ABSTRACT: To identify genes altered upon LIN-41 expression during reprogramming to induced pluripotent stem cells, human dermal fibroblasts were infected with combinations of GFP alone, OSK, OSKM, OSK+LIN-41, or OSK+let-7 inhibitor (transfected on days 1 and 6). After 11 days, TRA-1-60+ reprogramming cells were isolated as described in Tanabe et al 2013 or in the case of GFP-infected fibroblasts, GFP+ cells were collected. Total RNA was used for gene expression analysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE52052 | GEO | 2013/11/20

SECONDARY ACCESSION(S): PRJNA226594

REPOSITORIES: GEO

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Comparison of gene expression at day 11 of iPSC reprogramming with different reprogramming cocktails

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