Genomics

Dataset Information

0

Reinstatement of developmental stage-specific GATA4 enhancers controls the gene expression program in heart disease


ABSTRACT: Through integration of GATA4 genome-wide occupancy and RNA-seq dataset in embryonic conditional knockout heart, we identified a class of the master cardiac regulator GATA4 bound enhancers. With combinatorial assembly of chromatin signatures, we further refined that a unique type of fetal distal GATA4 enhancers enriched for H3K27ac, H3K4me1, but not for H3K4me3 and RNA polymerase II, are reinstated in adult hypertrophic heart.

ORGANISM(S): Mus musculus

PROVIDER: GSE52123 | GEO | 2014/08/13

SECONDARY ACCESSION(S): PRJNA226752

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2014-08-13 | E-GEOD-52123 | biostudies-arrayexpress
2014-01-01 | E-GEOD-52317 | biostudies-arrayexpress
2007-11-13 | E-GEOD-5500 | biostudies-arrayexpress
2006-08-12 | GSE5500 | GEO
2012-06-22 | E-GEOD-35151 | biostudies-arrayexpress
2014-01-01 | GSE52317 | GEO
2012-11-30 | E-GEOD-27329 | biostudies-arrayexpress
2014-02-06 | E-GEOD-44233 | biostudies-arrayexpress
2012-06-22 | GSE35151 | GEO
2021-07-01 | GSE156001 | GEO