Targeting PBK/TOPK decreases growth and survival of glioblastoma stem cells in vitro and attenuates tumor growth in vivo
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ABSTRACT: Gene knockdown of PBK led to decreased proliferation and sphere formation in the GSC cultures. Treatment of cells with different concentrations of HI-TOPK-032 almost completely abolished growth and proliferation and elicited a large increase in apoptosis
ORGANISM(S): Homo sapiens
PROVIDER: GSE53800 | GEO | 2015/06/16
SECONDARY ACCESSION(S): PRJNA233313
REPOSITORIES: GEO
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