CDH1 knockout in mice
Ontology highlight
ABSTRACT: Employing Cre/loxP technology, a mouse model of liver specific Cdh1 (E-cadherin) depletion was created (fl/fl | +/wt). Previously, the mice had already been compared to littermates with normal Ecadherin levels (fl/fl | wt/wt), using a broad range of laboratory methods (Serum parameters, long-term weight analysis, histology, western blot, etc.). To analyze the effect of Cdh1 (E-Cadherin) depletion on the liver homeostasis on the RNA-level over the course of 3 time-points, liver tissue was aquired from mice groups aged 1 week, 3 weeks and 6 weeks.
ORGANISM(S): Mus musculus
PROVIDER: GSE54234 | GEO | 2014/07/01
SECONDARY ACCESSION(S): PRJNA236013
REPOSITORIES: GEO
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