Transcriptomics

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Differential gene expression in 2 days old zebrafish after glucocerebrosidase (GBA1) morpholino-mediated knockdown


ABSTRACT: Gene expression signature was explored to identify gene targets regulate by dysfunctional glucocerebrosidase function. We found 131 upregulated genes and 63 downregulated genes. Some of the most upregulated (PON3, PLOD1) and downregulated (gpx-1b and complemewnt c9) genes were analyzed by q-PCR demonstrating the correct differential gene expression signature among control and morpholino-microinjected fish.

ORGANISM(S): Danio rerio

PROVIDER: GSE54754 | GEO | 2014/02/07

SECONDARY ACCESSION(S): PRJNA237550

REPOSITORIES: GEO

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