Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Microarray analysis of the testis from the aromatase overexpression transgenic and WT mice

ABSTRACT: To futher find the gene expression due to the aromatase overexpression in the mouse testis,we have employ whole genome microarray expression profiling as a discovery platform to identify genes compared to the wild type mice. The testes were taken from 5 month old aromatase overexpression mice and WT mice as control.

ORGANISM(S): Mus musculus

PROVIDER: GSE55254 | GEO | 2014/04/18

SECONDARY ACCESSION(S): PRJNA239006

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Microarray analysis of the testis from the aromatase overexpression transgenic and WT mice

Project description:To futher find the gene expression due to the aromatase overexpression in the mouse testis,we have employ whole genome microarray expression profiling as a discovery platform to identify genes compared to the wild type mice. The testes were taken from 5 month old aromatase overexpression mice and WT mice as control. We investigated genes that were significantly upregulated or downregulated in AROM+ mouse testis compared with WT testis. Two groups: 1) total RNA from three 5 month old AROM+ overexpression transgenic mice testes were collected and processed for microarray;2) total RNA from three 5 month old WT mice testes as control.

2014-04-18 | E-GEOD-55254 | biostudies-arrayexpress

mRNA-seq of gonads from adult zebrafish treated with aromatase inhibitor and control

Project description:To explore the transcriptional effects of aromatase inhibitors on sex differentiation of zebrafish, we exposed 3-month-old zebrafish (AB strain) to the third generation aromatase inhibitor Exemestane (CAS: 107868-30-4) and characterized transcript abundance among testes and ovaries after 32 days of drug exposure. After the drug treatment, we dissected zebrafish gonads, isolated polyA+ RNA and performed high-throughput RNA-Seq analysis.

2019-12-07 | GSE123439 | GEO

Microarray analysis of differential gene expression of whole testis extracts from transgenic Musashi-2 and transgenic Musashi-1 over-expression mice

Project description:Analysis of testis-specific over-expression of Musashi-1 and Musashi-2 at gene expression level. The hypothesis tested in the present study was that testis-specific over-expression of Musashi-1/Musashi-2 would result in differential gene expression profiles from the Wildtype control. Results provide important information of the genes affected by Musashi-2 overexpression during spermatogenesis. Total RNA obtained from whole adult testis of transgenic testis-specfic Musashi-1 and Musashi-2 overexpression mice compared to Wildtype (control) littermates. 4 replicates, 16 samples, 2 comparisons: Wt (Musashi-1) vs. TgMsi1 & Wt (Musashi-2) vs. TgMsi2

2014-07-12 | E-GEOD-59358 | biostudies-arrayexpress

RNA-seq of F1 mouse testis samples from differentlncRNA5251 modification groups

Project description:The goat of this project is to explore lncRNA5251 regulation spermatogenesis. We tried to search the mechanism oflncRNA5251 regulation spermatogenesis. RNA-seq of F1 mouse testis samples from different groups: 5NC, lncRNA5251 overexpression, 3NC, lncRNA5251 knockdown. The testes of mouse were transfected with virus with 5NC, lncRNA5251 overexpression, 3NC, lncRNA5251 knocdown letivirus.

2021-12-01 | GSE142725 | GEO

RNA-seq of F0 mouse testis samples from differentlncRNA5251 modification groups

Project description:The goat of this project is to explore lncRNA5251 regulation spermatogenesis. We tried to search the mechanism oflncRNA5251 regulation spermatogenesis. RNA-seq of F0 mouse testis samples from different groups: 5NC, lncRNA5251 overexpression, 3NC, lncRNA5251 knockdown. The testes of mouse were transfected with virus with 5NC, lncRNA5251 overexpression, 3NC, lncRNA5251 knocdown letivirus.

2021-12-01 | GSE142724 | GEO

Adult mouse testis

Project description:SAGE libraries generated from total testes of adult mouse males. Keywords = testis Keywords: other

2005-03-15 | GSE1939 | GEO

RNA-seq of F1 mouse testis samples from different lncRNA8276 modification groups

Project description:The goat of this project is to explore lncRNA8276 regulation spermatogenesis. We tried to search the mechanism oflncRNA8276 regulation spermatogenesis. RNA-seq of F1 mouse testis samples from different groups: 5NC, lncRNA8276 overexpression, 3NC, lncRNA8276 knockdown. The testes of mouse were transfected with virus with 5NC, lncRNA8276 overexpression, 3NC, lncRNA8276 knocdown letivirus.

2021-12-01 | GSE142795 | GEO

RNA-seq of F0 mouse testis samples from different lncRNA8276 modification groups

Project description:The goat of this project is to explore lncRNA8276 regulation spermatogenesis. We tried to search the mechanism oflncRNA8276 regulation spermatogenesis. RNA-seq of F0 mouse testis samples from different groups: 5NC, lncRNA8276 overexpression, 3NC, lncRNA8276 knockdown. The testes of mouse were transfected with virus with 5NC, lncRNA8276 overexpression, 3NC, lncRNA8276 knocdown letivirus.

2021-12-01 | GSE142793 | GEO

Expression profiling of BORIS knockout mice testis

Project description:To identify differentially expressed genes in Boris KO testis, gene expression profilings were performed with NIAID mouse customized arrays. Gene expressions of five biological replicates of Boris KO testis were compared to those of wild type testis. Total RNAs from WT and BORIS KO testes prepared from P14 mice were labelled with Cy5 and Cy3, respectively. Five sets of each genotype were studied.

2010-06-05 | E-GEOD-19162 | biostudies-arrayexpress

Adult mouse testis

Project description:SAGE libraries generated from total testes of adult mouse males. Keywords = testis Keywords: other

2005-03-14 | E-GEOD-1939 | biostudies-arrayexpress