WGBS data of pediatric B-cell acute leukemias
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ABSTRACT: We investigated DNA methylomes of 227 pediatric B-cell acute lymphoblastic leukemias (B-ALLs) using whole-genome bisulfite sequencing and high-definition microarrays, along with RNA expression profiles. The current study identified a link between DNA methylome of B-cell acute lymphoblastic leukemias (B-ALLs) and embryonic stem cell (ESC) bivalency, through which tumor cells can mimic the pluripotency of ESCs.
ORGANISM(S): Homo sapiens
PROVIDER: GSE56601 | GEO | 2015/02/23
SECONDARY ACCESSION(S): PRJNA244061
REPOSITORIES: GEO
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