Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Genome-wide profiling of the DNA methylation landscape at base-pair resolution in human neurological disorders (Bisulfite-Seq)

ABSTRACT: Whole genome bisulphite sequencing of 4 human neurological disorders.

ORGANISM(S): Homo sapiens

PROVIDER: GSE57359 | GEO | 2016/01/22

SECONDARY ACCESSION(S): PRJNA246326

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Genome-scale profiling of the DNA methylation landscape in human neurological disorders (BeadChip)

Project description:Genome-scale DNA methylation profiling using the Infinium DNA methylation BeadChip platform and samples from 4 human neurological disorders.

2016-01-22 | GSE57360 | GEO

Next Generation Mendelian Genetics: Hereditary Neurological Disorders

Project description:Next Generation Mendelian Genetics: Hereditary Neurological Disorders

| PRJNA236332 | ENA

Genome-wide profiling of the functional DNA methylation landscape at base-pair resolution in human cancer types [BS-seq]

Project description:Whole genome bisulphite sequencing of 13 human cancer samples and 9 normal controls. The main goal is to find the Diffrenetial methylated regions (DMR) at Genome wide level in different tissues and cancer types

2016-01-08 | GSE52271 | GEO

Genome-scale profiling of the DNA methylation landscape in human neurological disorders

Project description:Genome-scale profiling of the DNA methylation landscape in human neurological disorders

| PRJNA246325 | ENA

Genetics and Functional Studies of Autosomal Recessive Neurological Disorders

Project description:Genetics and Functional Studies of Autosomal Recessive Neurological Disorders

| PRJNA971741 | ENA

Genetics and Functional Studies of Autosomal Recessive Neurological Disorders

Project description:Genetics and Functional Studies of Autosomal Recessive Neurological Disorders

| PRJNA971740 | ENA

Genome-wide profiling of the functional DNA methylation landscape at base-pair resolution in human cancer types [BS-seq]

2016-01-08 | E-GEOD-52271 | biostudies-arrayexpress

Genome-wide profiling of the DNA methylation landscape at base-pair resolution in human acute myeloid leukemia cell lines.

Project description:Whole genome bisulphite sequencing of 2 human cancer cell line samples. One cell line harbours a heterozygous mutation in the DNA methyl-transferase DNMT3a, a common alteration observed in AML patients. The main goal is to find the differentially methylated regions (DMR) at genome-wide level between the mutant and a wild-type cell lines to elucidate the effect of the mutation and the implication in leukomogenesis.

2015-10-07 | GSE62300 | GEO

Epigenetic alterations of a DNMT3B-mutant ICF patient at base-pair resolution

Project description:The immunodeficiency, centromere instability and facial anomalies (ICF) syndrome is associated with mutation of the DNA methyl-transferase DNMT3B, resulting in a reduction of enzyme activity. Aberrant expression of immune system genes and hypomethylation of pericentromeric regions accompanied by chromosomal instability were determined as alterations driving the disease phenotype. However, so far only technologies capable of analyzing single loci were applied to determine epigenetic alterations in ICF patients. In the current study, we performed whole-genome bisulphite sequencing to assess alteration in DNA methylation at base-pair resolution. Whole-genome bisulphite sequencing was performed to assess alteration in DNA methylation of one ICF patient and one healthy control sample at base-pair resolution.

2012-04-25 | E-GEOD-37578 | biostudies-arrayexpress

Epigenetic alterations of a DNMT3B-mutant ICF patient at base-pair resolution

2012-04-26 | GSE37578 | GEO