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Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes

ABSTRACT: We report the profiling of induced mRNA transcripts in two C. elegan replicate populations -- WT (N2) and mutant strain with deficient HLH30. Both strains were fed either OP50 strain of e-coli (normal feed) or S. aureus

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE57739 | GEO | 2015/06/04

SECONDARY ACCESSION(S): PRJNA247976

REPOSITORIES: GEO

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Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes

Project description:We report the profiling of induced mRNA transcripts in two C. elegan replicate populations -- WT (N2) and mutant strain with deficient HLH30. Both strains were fed either OP50 strain of e-coli (normal feed) or S. aureus Examination of infected versus uninfected wildtype and mutant lawns of animals

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Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes.

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