Genomics

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MicroRNAs Involved in Aging of the Lateral Wall of the Cochlear Duct


ABSTRACT: Age-related hearing loss is a progressive sensorineural hearing loss that occurs as people get older. Degeneration of the organ of Corti and atrophy of the lateral wall of the cochlear duct (or scala media) in the inner ear are the two primary causes. MicroRNAs (miRNAs), a class of short non-coding RNAs that regulate the expression of mRNA/protein targets, are important regulators of cellular senescence and aging. We examined the change of miRNA gene expression profiles in the lateral wall of the cochlear duct in two mouse strains during aging

ORGANISM(S): synthetic construct Mus musculus

PROVIDER: GSE57782 | GEO | 2014/10/01

SECONDARY ACCESSION(S): PRJNA248086

REPOSITORIES: GEO

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