Targets of pharmacological histone deacetylase inhibition in human umbilical vein endothelial cells
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ABSTRACT: We and others have previously reported the paradoxical downregulation of endothelial nitric oxide synthase (eNOS, NOS3) steady-state mRNA by pharmacological histone deacetylase (HDAC) inhibitors. This microarray experiment was designed to identify novel targets of an HDAC inhibitor (trichostatin A (TSA), 500 nM, 24h, Sigma) in primary human endothelial cells (human umbilical vein endothelial cells, HUVEC). Keywords: gene expression profiling, paired samples, dichotomous conditions
ORGANISM(S): Homo sapiens
PROVIDER: GSE5856 | GEO | 2006/09/20
SECONDARY ACCESSION(S): PRJNA97263
REPOSITORIES: GEO
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