Transcriptomics

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Effect of Gnas knockout on mouse skin


ABSTRACT: Analysis of skin lesions from adult mice with epidermal conditional deletion of heterotrimeric G protein Galpha s in cytokeratin 14 positive cells, compared with control mouse skin. Epidermal Gnas ablation leads to skin defects, including basal cell carcinoma (BCC). Results provide insight into role of Galpha s in the regulation of stem cells from the skin.

ORGANISM(S): Mus musculus

PROVIDER: GSE58894 | GEO | 2014/06/28

SECONDARY ACCESSION(S): PRJNA253825

REPOSITORIES: GEO

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