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Affymetrix expression profile array data of miR-206 affected genes in left superior fat pads in canines

ABSTRACT: Mongrel dogs of either sex were randomly divided into 2 groups: 1) infection with control lentiviruses group (lenti-control, n = 6), in which control lentiviruses were injected into left superior fat pads;2) only infection with miR-206 overexpressed lentiviruses group (lenti-miR-206, n = 6), in which miR-206 lentiviruses were injected into left superior fat pads. We used microarrays to detail the global programme of mRNA expression underlying miR-206 overexpression and identified distinct classes of up-regulated and down-regulated genes during this process.

ORGANISM(S): Canis lupus familiaris

PROVIDER: GSE59197 | GEO | 2014/07/09

SECONDARY ACCESSION(S): PRJNA254714

REPOSITORIES: GEO

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Affymetrix expression profile array data of miR-206 affected genes in left superior fat pads in canines

Project description:Mongrel dogs of either sex were randomly divided into 2 groups: 1) infection with control lentiviruses group (lenti-control, n = 6), in which control lentiviruses were injected into left superior fat pads;2) only infection with miR-206 overexpressed lentiviruses group (lenti-miR-206, n = 6), in which miR-206 lentiviruses were injected into left superior fat pads. We used microarrays to detail the global programme of mRNA expression underlying miR-206 overexpression and identified distinct classes of up-regulated and down-regulated genes during this process. Microarray-based mRNA expression profiling was performed of miR-206 overexpressed group and control group using the Affymetrix Array (CA, USA). Equal quantities of RNAs from 3 dogs were mixed to generate one sample for each experimental group.

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