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MiRNA expression during UCB-CD34 cells erythropoiesis

ABSTRACT: We investigated the miRNA expression in ex vivo human erythroid cultures from umbilical cord blood (UCB)-derived CD34 cells. Hypothetically, the decline of certain miRNAs may promote erythropoiesis by unblocking expression of key functional proteins while the up-regulation of other miRNAs may block commitment to non-erythroid lineages. Therefore, discovering the patterns and sequence of miRNA expression during hematopoietic differentiation will provide insights about the functional roles of these tiny noncoding genes. Keywords: miRNA expression profiling

ORGANISM(S): Homo sapiens

PROVIDER: GSE6000 | GEO | 2007/04/01

SECONDARY ACCESSION(S): PRJNA97495

REPOSITORIES: GEO

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