Methylation profiling

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Global loss of DNA methylation uncovers intronic enhancers in genes


ABSTRACT: We used HCT116 colorectal cancer cells with and without mutations in DNA methyltransferases (resulting in a 95% reduction in global DNA methylation levels) to study the relationship between DNA methylation, histone modifications, and gene expression. (The double knockout cell line is called DKO1)

ORGANISM(S): Homo sapiens

PROVIDER: GSE60106 | GEO | 2014/09/10

SECONDARY ACCESSION(S): PRJNA257496

REPOSITORIES: GEO

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