Transcriptomics

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Expression data of neural progenitor cells differentiation from human embryonic stem cells


ABSTRACT: Mocetinostat (MGCD) which is a kind of histone deacetylase inhibitors (HDACi) promotes human embryonic stem cells (hESCs) differentiation towards neural progenitor cells (NPCs). Application of HDAC inhibitors (HDACi) increased the expression of neuroectodermal markers once neural differentiation was initiated, thereby leading to more NPC generation. We used microarrays to detail the global gene expression during NPC differentiaton upon MGCD treatment and identified the transcript changes effected by MGCD during this process.

ORGANISM(S): Homo sapiens

PROVIDER: GSE61050 | GEO | 2014/09/03

SECONDARY ACCESSION(S): PRJNA260157

REPOSITORIES: GEO

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