Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome profiling of Normal and Cancerous Prostate Cells [expression array]

ABSTRACT: To identify aberrant non coding gene expression in prostate cancer, we performed expression profiling of normal prostate epithelial cells (PrEC) and the prostate cancer cell line LNCaP using Affymetrix HuGene 2.0 ST expression arrays. These expression arrays were validated by expression qPCR of selected genes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE61790 | GEO | 2018/09/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Transcriptome profiling of Normal and Cancerous Prostate Cells using Affymetrix Human Transcriptome Array 2.0

Project description:To identify aberrant expression of transcripts in prostate cancer, we performed global gene and transcript expression profiling of normal prostate epithelial cells (PrEC) and the prostate cancer cell line LNCaP using Affymetrix Human Transcriptome 2.0 expression arrays.

2018-09-01 | GSE62497 | GEO

Real-time quantitative PCR analysis of Normal and Cancerous Prostate Cells [RT-PCR]

Project description:To validate a panel of selected genes expression in prostate cancer, we performed expression profiling of normal prostate epithelial cells (PrEC) and the prostate cancer cell line LNCaP using qPCR.

2018-09-01 | GSE62409 | GEO

MeDIP and ChIP-on-chip data from normal Prostate epithelial cells (PrEC) and the LNCaP cancer cell line

Project description:To identify genomic regions which display concordant epigenetics alterations in prostate cancer, we performed MeDIP and ChIP-on-chip profiling of normal prostate epithelial cells (PrEC) and the prostate cancer cell line LNCaP. These promoter arrays were integrated with expression arrays of the same cells to discover and characterise regions of Long Range Epigenetic Silencing (LRES) in prostate cancer.

2010-01-04 | GSE19600 | GEO

Expression data from normal Prostate epithelial cells (PrEC) and the LNCaP cancer cell line

Project description:To identify genomic regions which display concordant gene expression in prostate cancer, we performed expression profiling of normal prostate epithelial cells (PrEC) and the prostate cancer cell line LNCaP. These expression arrays were integrated ChIP-on-chip studies of active and repressive epigenetic marks in same cells to discover and characterise regions of Long Range Epigenetic Silencing (LRES) in prostate cancer.

2010-01-04 | GSE19725 | GEO

Genomic DNA in Normal and Cancerous Prostate Cells

Project description:To investiagate copy number differences between PrEC and LNCaP cells, each was DNA sequenced. One PrEC sample, a normal cell line. One LNCaP sample, a cancer cell line.

2012-11-30 | E-GEOD-38674 | biostudies-arrayexpress

Genomic DNA in Normal and Cancerous Prostate Cells

Project description:To investiagate copy number differences between PrEC and LNCaP cells, each was DNA sequenced.

2012-11-30 | GSE38674 | GEO

Expression data from uncastrasion and castration tumor from LNCAP Orhotopic xenograft models of prostate cancer

Project description:To identify molecular singnal alterations between androgen dependent prostate cancer and castration resistant prostate cancer, we performed interspecies comparative microarray analyses using RNAs prepared from uncastrasion and castration tumor from LNCAP Orhotopic xenograft models of prostate cancer. microarray data from uncastrasion and castration tumor revealed that the gene expression profile is most significantly altered in between androgen dependent prostate cancer and castration resistant prostate cancer. Comparative analyses of LNCAP Orhotopic xenograft models of prostate cancer showed that genes involved in androgen dependent and androgen independent tumor were significantly altered. We prepared RNA samples from 4 samples uncastrasion and 4 samples castration tumors from LNCAP Orhotopic xenograft models of prostate cancer . High-quality RNA samples were subjected to microarray analysis using the Affymetrix Human Gene 2.0 ST platform, and only those results that passed examinations for quality assurance and quality control of the Human Gene 2.0 ST arrays were retrieved. In total, we obtained gene expression profiles from the following samples: 4 samples uncastrasion and 4 samples castration tumors

2013-04-20 | E-GEOD-46218 | biostudies-arrayexpress

Chromatin Looping of Normal and Cancerous Prostate Cells

Project description:Mapping the locations of the DNA binding protein CTCF genome-wide to assess its colocalisation with expression domain boundaries. One PrEC sample, a normal cell line. One LNCaP sample, a cancer cell line.

2012-11-30 | E-GEOD-38684 | biostudies-arrayexpress

H3K27me3 Marks in Normal and Cancerous Prostate Cells

Project description:The histone modification H3K27me3 is representative of silenced regions of the genome. Changes between the normal and cancer state were investigated. Three PrEC samples, a normal cell line. Four LNCaP sample, a cancer cell line. Technical replicates.

2012-11-30 | E-GEOD-38683 | biostudies-arrayexpress

Expression Analysis of Normal and Cancerous Prostate Cells

Project description:Strand-specific RNA sequencing was done on a normal and a cancer cell line to examine how isoforms are used differently between these two states. One PrEC sample, a normal cell line. One LNCaP sample, a cancer cell line.

2012-11-30 | E-GEOD-38676 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data