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Induction of ER stress in HCT116 colon cancer cells

ABSTRACT: To investigate the role of p53 and DICER in the induction of ER stress, wildtype, p53 knockout or DICER mutant HCT116 colon cancer cells were treated with the ER stress inducers tunicamycin or brefeldin A for 24 hours. Microarray analysis was used to determine changes in gene expression associated with the induction of ER stress, and to compare this induction in wildtype, p53 knockout or DICER mutant HCT116 colon cancer cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE63252 | GEO | 2015/04/01

SECONDARY ACCESSION(S): PRJNA267109

REPOSITORIES: GEO

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Induction of ER stress in HCT116 colon cancer cells

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