Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Genome-wide analysis of wild type and gemin2 mutant plants exposed to cold

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE63407 | GEO | 2015/08/03

SECONDARY ACCESSION(S): PRJNA267678

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Genome-wide analysis of wild type and gemin2 mutant plants exposed to cold

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-08-03 | E-GEOD-63407 | biostudies-arrayexpress

Genome-wide analysis of wild type and prmt5 mutant plants

Project description:This SuperSeries is composed of the SubSeries listed below.

2020-04-28 | GSE149431 | GEO

Genome-wide analysis of wild type and gemin2 mutant plants [cold exposure]

Project description:The goal of this study was to compare the transcriptional profile (RNA-seq) of wild type and gemin2 Arabidopsis mutants plants exposed to 10ºC for 0, 1 and 24 hours.

2015-08-03 | GSE63406 | GEO

Genome-wide analysis of wild type and gemin2 mutant plants [cold exposure]

Project description:The goal of this study was to compare the transcriptional profile (RNA-seq) of wild type and gemin2 Arabidopsis mutants plants exposed to 10ºC for 0, 1 and 24 hours. WT and gemin2 mutant plants were grown for nine days under continuous white light at 22 degrees centigrades or exposed for 1 or 24 h to 10ºC on the 9th day, before harvesting. Then the transcriptional profile of these plants was analyzed using RNA-seq.

2015-08-03 | E-GEOD-63406 | biostudies-arrayexpress

Genome wide RNA-seq analysis of Smchd1 wild type and mutant

Project description:This SuperSeries is composed of the SubSeries listed below.

2013-07-03 | GSE44669 | GEO

Genome wide RNA-seq analysis of Smchd1 wild type and mutant

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-07-03 | E-GEOD-44669 | biostudies-arrayexpress

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

Project description:Tumor suppressor p53 (TP53) is frequently mutated in cancer, often resulting not only in loss of its tumor-suppressive function but also acquisition of dominant-negative and even oncogenic gain-of-function traits. While wild-type p53 levels are tightly regulated, mutants are typically stabilized in tumors, which is crucial for their oncogenic properties. Here, we systematically profiled the factors that regulate protein stability of wild-type and mutant p53 using marker-based genome-wide CRISPR screens. Most regulators of wild-type p53 also regulate p53 mutants, except for p53 R337H regulators, which are largely private to this mutant. Mechanistically, FBXO42 emerged as a positive regulator for a subset of p53 mutants, working with CCDC6 to control USP28-mediated mutant p53 stabilization. Additionally, C16orf72/HAPSTR1 negatively regulates both wild-type p53 and all tested mutants. C16orf72/HAPSTR1 is commonly amplified in breast cancer, and its overexpression reduces p53 levels in mouse mammary epithelium leading to accelerated breast cancer. This study offers a network perspective on p53 stability regulation, potentially guiding strategies to reinforce wild-type p53 or target mutant p53 in cancer.

| S-SCDT-10_1038-S44320-024-00032-X | biostudies-other

Genome-wide analysis of wild type and prmt5 mutant plants

Project description:Genome-wide analysis of wild type and prmt5 mutant plants

| PRJNA628674 | ENA

Genome-wide analysis of wild type and prmt5 mutant plants (Experiment B)

Project description:The goal of this study was to compare the transcriptional profile (RNA-seq) of wild type and prmt5 Arabidopsis mutants plants grown under continuous white light at 22 degrees centigrades for 9 days

2020-04-28 | GSE149430 | GEO

Genome-wide analysis of wild type and prmt5 mutant plants (Experiment A)

Project description:The goal of this study was to compare the transcriptional profile (RNA-seq) of wild type and prmt5 Arabidopsis mutants plants grown under continuous light at 22 degrees centigrades.

2020-04-28 | GSE149429 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data