Transcriptomics

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Cisplatin-induced gene expression changes in A549 NSCLC cells


ABSTRACT: Affymetrix high-density oligonucleotide microarray analysis was performed to analyse cisplatin-induced gene expression changes in A549 NSCLC cells. Cells were treated with 50 µM of cisplatin for 1 hour and incubated for a further 10 hours in drug-free media before the gene expression changes were investigated. Results show that cisplatin induced changes in the expression of genes involved in apoptosis, cell cycle control, DNA repair and transcription. Keywords: drug response

ORGANISM(S): Homo sapiens

PROVIDER: GSE6410 | GEO | 2007/12/01

SECONDARY ACCESSION(S): PRJNA99547

REPOSITORIES: GEO

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