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A ChIP-seq spike-in method enables detection of global histone modification changes across the genome

ABSTRACT: This study outlines a method that dramatically alters the interpretation of ChIP-seq data and will improve the quantitative comparison of histone modification maps across biological contexts or across various conditions within a given biological context.

ORGANISM(S): Homo sapiens

PROVIDER: GSE64243 | GEO | 2016/01/31

SECONDARY ACCESSION(S): PRJNA270645

REPOSITORIES: GEO

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A ChIP-seq spike-in method enables detection of global histone modification changes across the genome

Project description:This study outlines a method that dramatically alters the interpretation of ChIP-seq data and will improve the quantitative comparison of histone modification maps across biological contexts or across various conditions within a given biological context.

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"The Wild West of Spike-in Normalization": Benchmarking the ChIP-seq spike-in normalization method

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COVID-19 Spike Protein Induced Phononic Modification in Antibody-Coupled Graphene for Viral Detection Application.

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