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Comparison of gene expression profiles between the CD110+ tumor initiating cells from primary colorectal tumors and their liver metastases.

ABSTRACT: We established an in vivo model of organ-specific colorectal cancer metastasis and demonstrated that the CD110+ tumor initiating cells contribute for colorectal liver metastasis. To gain a deeper understanding of its metastatic capacity, we performed a genome-wide transcriptome analysis on the CD110+ tumor cells derived from primary colon xenografts and their matched liver metastases. Results provide important information of the responses of the CD110+ cells during the process of liver colonization.

ORGANISM(S): Homo sapiens

PROVIDER: GSE64595 | GEO | 2015/01/01

SECONDARY ACCESSION(S): PRJNA271374

REPOSITORIES: GEO

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Comparison of gene expression profiles between the CD110+ tumor initiating cells from primary colorectal tumors and their liver metastases.

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