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Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for atrial fibrillation

ABSTRACT: We identified 177 lncRNAs and 153 mRNAs that were differentially expressed (≥ 2-fold change), indicating that many lncRNAs are significantly upregulated or downregulated in AF. Among these, NONHSAT040387 and NONHSAT098586 were the most up-regulated and downregulated lncRNAs, and were selected for validation via quantitative PCR. GO analysis and KEGG pathway were applied to exploring potential lncRNAs function, identifying several pathways were alerted in atrial fibrillation pathogenesis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE64904 | GEO | 2016/01/01

SECONDARY ACCESSION(S): PRJNA272476

REPOSITORIES: GEO

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Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for atrial fibrillation

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