Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression.
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ABSTRACT: We characterized the marine natural product cortistatin A (CA) as an inhibitor of CDK8 to determine whether pharmacologic inhibition of CDK8 regulates super-enhancer function and inhibits AML proliferation. In this series, we examine the transcriptional effect on insensitive HCT116 cells of 3hrs exposure to CA.
ORGANISM(S): Homo sapiens
PROVIDER: GSE65030 | GEO | 2015/09/25
SECONDARY ACCESSION(S): PRJNA273294
REPOSITORIES: GEO
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