Sumoylation-deficient bone marrow derived dendritic cells transcriptomic analysis after LPS stimulation
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ABSTRACT: Bone marrow derived dendritic cells were generated from Ubc9[fl;-] and Ubc9[+/+] mice. After in vitro derivation in the presence of GM-CSF, dendritic cells were treated with tamoxifen for four days to cause CreERT2 activation, and induce Ubc9 floxed allele deletion. This allowed comparative transcriptomic analysis of Ubc9[+/+] and Ubc9[-/-] dendritic cells unstimulated or stimulated with 10ng/ml LPS for one hour and six hours.
ORGANISM(S): Mus musculus
PROVIDER: GSE66178 | GEO | 2015/12/14
SECONDARY ACCESSION(S): PRJNA276071
REPOSITORIES: GEO
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