Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Circadian rhythm in NIH3T3 cells

ABSTRACT: Identification of cyclical expressed coding and non-coding genes during the circadian rhythm in NIH3T3 cells. NIH3T3 cells were synchronized for their circadian rhythm and RNA sequencing were performed at several time points along the rhythm. This data was used to identify cyclical expressed genes as well as long intergenic non-coding RNAs.

ORGANISM(S): Mus musculus

PROVIDER: GSE66243 | GEO | 2015/12/31

SECONDARY ACCESSION(S): PRJNA276179

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Shared Molecules

Only show the datasets with similarity scores above: 0.5

Threshold

0.5

Similar Datasets

Circadian rhythm in NIH3T3 cells

Project description:Identification of cyclical expressed coding and non-coding genes during the circadian rhythm in NIH3T3 cells. NIH3T3 cells were synchronized for their circadian rhythm and RNA sequencing were performed at several time points along the rhythm. This data was used to identify cyclical expressed genes as well as long intergenic non-coding RNAs. NIH3T3 cells were synchronized with 100 nM Dexamethasone for 2 hours, then medium was changed to normal culture medium (0h). Every 4 hours cells were harvested, RNA isolated and RNAseq performed.

2015-12-31 | E-GEOD-66243 | biostudies-arrayexpress

Circadian rhythm in clock mutants

Project description:Circadian rhythm in clock mutants

| PRJNA93919 | ENA

Circadian rhythm in Clock mutant and Cry deficient mice

Project description:Molecular analysis of circadian rhythm in mice. Liver tissue of wildtype, Clock mutant and Cry deficient C57BL/6 8- to 10-week-old male mice examined. Keywords = circadian rhythm Keywords: other

2003-11-08 | GSE454 | GEO

Effect of d-alanine on circadian rhythm

Project description:To investigate the effect of d-ala on circadian rhythm.

2023-12-28 | GSE227755 | GEO

Regulatory T cells in hepatic circadian rhythm

Project description:Regulatory T cells (Treg cells) are important to maintain self-tolerance. In tissues, Treg cells can perform non-classical functions, for example, they are implicated in regulating metabolic processes in the adipose tissue. Their function in the liver is less well understood. We found here that Treg cells are important to secure the peripheral hepatic circadian rhythm of core-clock regulators and clock-controlled genes. Undisturbed metabolism in the liver required the presence of Treg cells and was especially important in the early postnatal phase, a distinct time period at around day 10, when the liver had not fully matured and Treg cells proliferated and accumulated in the liver-tissue. Our findings highlight a critical role for Treg cells to establish and maintain liver homeostasis.

2018-08-29 | PXD005047 | Pride

CIRCADIAN RHYTHM REPROGRAMMING DURING LUNG INFLAMMATION

Project description:CIRCADIAN RHYTHM REPROGRAMMING DURING LUNG INFLAMMATION

| PRJNA255326 | ENA

Exploring the transcriptional landscape of plant circadian rhythms using genome tiling arrays

Project description:A casual look at the behavior and function of animals and plants clearly shows that many physiological processes are periodic and tied to cyclical changes in a day. As suggested by the persistence of some rhythms in the absence of external cues, organisms are able to anticipate changes in the daily environment with an internal oscillator know as the circadian clock. Transcription is an important mechanism in maintaining these oscillations. Here we explore, using whole genome tiling arrays, the extent of rhythmic expression patterns genome wide, with an unbiased analysis of coding and noncoding regions of the Arabidopsis genome. As in previous studies, we detected a circadian rhythm for approximately 25% of the protein coding genes in the genome. With an unbiased interrogation of the genome, extensive rhythmic introns were detected predominantly in phase with adjacent rhythmic exons creating a transcript that if translated would be expected to produce a truncated protein. In some cases such as the MYB transcription factor PHOSPATE STARVATION RESPONSE1, an intron was found to exhibit a circadian rhythm while the remainder of the transcript was otherwise arrhythmic. In addition to several known non-coding transcripts including miRNA, trans-acting siRNA, and snoRNA, greater than one thousand intergenic regions were detected as circadian clock regulated, many of which have no predicted function, either coding or non-coding. Nearly 7% of the protein coding genes produced rhythmic antisense transcripts, often for genes whose sense strand was not similarly rhythmic. This study revealed widespread circadian clock regulation of the Arabidopsis genome extending well beyond the protein coding transcripts measured to date. This suggests a greater level of structural and temporal dynamics than previously known.

2008-12-06 | GSE13814 | GEO

Circadian rhythm disruption is associated with skeletal muscle dysfunction within the blind Mexican Cavefish

Project description:Circadian rhythm disruption is associated with skeletal muscle dysfunction within the blind Mexican Cavefish

2023-01-13 | MSV000091062 | MassIVE

Renal circadian rhythm dysregulation in lupus nephritis

Project description:Renal circadian rhythm dysregulation in lupus nephritis

| PRJNA545270 | ENA

Effect of d-alanine on circadian rhythm

Project description:Effect of d-alanine on circadian rhythm

| PRJNA946765 | ENA