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Effects of ischemia reperfusion injury or nephrectomy on mouse lung

ABSTRACT: Experiments in rodents have shown that kidney ischemia/reperfusion injury (IRI) facilitates lung injury and inflammation. To identify potential ischemia-specific lung molecular pathways involved, we conducted global gene expression profiling of lung 6 or 36 hours following 1) bilateral kidney IRI, 2) bilateral nephrectomy (BNx), and 3) sham laparotomy in C57BL/6J mice. Total RNA from whole lung was isolated and hybridized to 430MOEA (22,626 genes) GeneChips (n=3/group). Keywords: different time points after different treatments

ORGANISM(S): Mus musculus

PROVIDER: GSE6730 | GEO | 2007/05/30

SECONDARY ACCESSION(S): PRJNA99001

REPOSITORIES: GEO

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Transcription profiling of mouse lung to investigate effects of ischemia reperfusion injury or nephrectomy

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