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A master virulence regulator of S. aureus inactivated during carriage in man

ABSTRACT: It remains unclear how the bacterial populations which colonise many healthy humans occasionally give rise to severe disease. Staphylococcus aureus represents one such population. Here we describe mutations in invasive S. aureus which arose during human colonisation and inactivated rsp, a transcription factor. RNA-Seq was used to generate mRNA profiles of genes controlled by rsp.

ORGANISM(S): Staphylococcus aureus

PROVIDER: GSE67448 | GEO | 2016/05/03

SECONDARY ACCESSION(S): PRJNA279958

REPOSITORIES: GEO

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