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Liver samples of Pemt-/- and Pemt+/+ mice under high fat-high-sucrose (HFHS) diet

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Mus musculus

PROVIDER: GSE67793 | GEO | 2015/04/14

SECONDARY ACCESSION(S): PRJNA280947

REPOSITORIES: GEO

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Epigenome analysis of liver tissues from Pemt-/- and Pemt+/+ under high fat-high sucrose (HFHS) diet

Project description:Genome wide DNA methylation profiling of liver tissues from Pemt-/- and Pemt+/+ under HFHS diets.

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Expression data from liver samples of Pemt-/- and Pemt+/+ mice under high fat-high-sucrose (HFHS) diet

Project description:We used microarrays to detail the global programme of gene expression in the liver of Pemt-/- and Pemt+/+ under HFHS diets.

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Expression data from liver samples of Pemt-/- and Pemt+/+ mice under high fat-high-sucrose (HFHS) diet

Project description:We used microarrays to detail the global programme of gene expression in the liver of Pemt-/- and Pemt+/+ under HFHS diets. Liver sample of Pemt-/- and Pemt+/+ mice under HFHS for 1, 2, 3, 4 weeks were used for RNA extraction and hybridization on Affymetrix microarrays. Genes in liver of Pemt-/- mice, successively suppressed compared with Pemt+/+ mice, were obtained.

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Epigenome analysis of liver tissues from Pemt-/- and Pemt+/+ under high fat-high sucrose (HFHS) diet

Project description:Genome wide DNA methylation profiling of liver tissues from Pemt-/- and Pemt+/+ under HFHS diets. Pemt-/- and Pemt+/+ mice were fed HFHS from 5 to 25 weeks of age and liver tissues were obtained at 25 weeks. Bisulphite converted DNAs were enriched with EpiXplore Methylation DNA Enrichment Kit (Clontech). Genomic DNA libraries was prepared by TruSeq ChIP Sample Preparation Kit.

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Liver samples of Pemt-/- and Pemt+/+ mice under high fat-high-sucrose (HFHS) diet

Project description:Liver samples of Pemt-/- and Pemt+/+ mice under high fat-high-sucrose (HFHS) diet

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