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Gene expression analysis of bronchial epithelial cells stimulated by different airway pathogens.

ABSTRACT: Bronchial epithelial cells represent the first line of defense against invading airborne pathogens. They are important contributors to innate mucosal immunity and provide a variety of anti-microbial effectors. To investigate the role of epithelial cells upon infection of airway pathogens, we stimulated BEAS-2B cells for 4 h with UV-inactivated bronchial pathogens including Staphylococcus aureus, Pseudomonas aeruginosa and Respiratory Syncitial Virus (RSV) that among other receptors can strongly activate TLR2, TLR4 and TLR3, respectively. Keywords: expression profiling, response to pathogens

ORGANISM(S): Homo sapiens

PROVIDER: GSE6802 | GEO | 2007/02/27

SECONDARY ACCESSION(S): PRJNA99201

REPOSITORIES: GEO

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