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Expression data from predose and postdose rat blood after acetaminophen treatment

ABSTRACT: Predose and postdose gene expression profiles of blood samples of five most susceptible and five most resistant rats to acetaminophen-induced hapatotoxicity were determined by microarray analysis. Four out of ten selected genes were found to be reproducibly in real-time PCR with independent set animals to predict the susceptible individuals to acetaminophen-induced hapatotoxicity.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE68065 | GEO | 2015/09/07

SECONDARY ACCESSION(S): PRJNA281645

REPOSITORIES: GEO

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Expression data from predose and postdose rat blood after acetaminophen treatment

Project description:Predose and postdose gene expression profiles of blood samples of five most susceptible and five most resistant rats to acetaminophen-induced hapatotoxicity were determined by microarray analysis. Four out of ten selected genes were found to be reproducibly in real-time PCR with independent set animals to predict the susceptible individuals to acetaminophen-induced hapatotoxicity. We combined gene expression profiles of predose and postdose rat blood to predict the susceptible individuals to acetaminophen-induced hapatotoxicity.

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