Transcriptomics

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Alternative splicing in genes encoding adhesion- and motility-related proteins in breast cancer


ABSTRACT: In this study, combining 1) RNA-Sequencing on MCF-7 cell line, 2) a new computational approach to identify splice isoforms and 3) an extensive experimental validation (in vitro - on MCF-10, MCF-7 and MDA-MB-231 – and ex vivo – on human breast cancer tissues) we investigated simultaneously gene expression and alternative splicing in genes encoding for adhesion and motility-related molecules-, including Semaphorins and their receptors and co-receptors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE68228 | GEO | 2015/06/01

SECONDARY ACCESSION(S): PRJNA282078

REPOSITORIES: GEO

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