Transcriptomics

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Identification of down-stream targets of Notch signaling within the developing mosue kidney collecting ducts.


ABSTRACT: Notch signaling deficient kidney collecting ducts may serve as a useful resource to identify principal cell lineage and intercalated lineage specific factors since they develop a reduced number of principal cells and an increased number of intercalated cells compared with wild type kidney collecting ducts. We compared RNA from three E18.5 mouse kidneys per group: HoxB7Cre;RBPJf/-;Rosa+/Eyfp (Notch signaling deficient; mutant) versus RBPJf/f;Rosa+/Eyfp (wild type).

ORGANISM(S): Mus musculus

PROVIDER: GSE68389 | GEO | 2017/02/27

SECONDARY ACCESSION(S): PRJNA282590

REPOSITORIES: GEO

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